Molecular Interactions of Cannabinoid Receptor Interacting Protein 1 A and B with Cannabinoid Receptor 1
نویسندگان
چکیده
منابع مشابه
CB1 cannabinoid receptor activity is modulated by the cannabinoid receptor interacting protein CRIP 1a.
The CB1 cannabinoid receptor is a G-protein coupled receptor that has important physiological roles in synaptic plasticity, analgesia, appetite, and neuroprotection. We report the discovery of two structurally related CB1 cannabinoid receptor interacting proteins (CRIP1a and CRIP1b) that bind to the distal C-terminal tail of CB1. CRIP1a and CRIP1b are generated by alternative splicing of a gene...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2017
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2016.11.331